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High concernPreservative

Bronopol

Formaldehyde releaserKnown carcinogenSkin irritantAllergen

What it is

A brominated aliphatic alcohol that generates formaldehyde on decomposition and can form carcinogenic nitrosamines in the presence of amine compounds.

What it does

Antimicrobial preservative for cosmetics, pharmaceuticals, and industrial systems.

Why it’s a concern

Besides releasing formaldehyde, bronopol can react with secondary or tertiary amines (triethanolamine, DEA, TEA) in the same formulation to form N-nitrosamines, several of which are classified by IARC as probable human carcinogens. The EU restricts bronopol to rinse-off products at 0.1% maximum and disallows it in products with amines.

Also known as

2-bromo-2-nitropropane-1,3-diol

CAS numbers

52-51-7

Commonly found in

shampoolotioncleansers

Safer alternatives

  • sodium benzoate
  • phenoxyethanol
  • glyceryl caprylate

Related chemical families

Formaldehyde

Sources

  • SCCS Opinion on Bronopol
  • IARC Monographs on Nitrosamines