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High concernPreservative

Butylparaben

ParabenEndocrine disruptorReproductive toxicant

What it is

The n-butyl ester of para-hydroxybenzoic acid. Among the most estrogenic parabens in common use due to its longer alkyl chain.

What it does

Preservative used in cosmetics, pharmaceuticals, and some foods to prevent microbial spoilage.

Why it’s a concern

Butylparaben showed the strongest binding affinity to estrogen receptors among the parabens tested by Routledge et al. in 1998 (Toxicology and Applied Pharmacology), roughly 10,000 times weaker than estradiol but present in far greater amounts in daily exposure. Animal studies link it to reduced sperm counts and altered testosterone. Denmark banned butyl- and propylparaben in products for children under three in 2011, a precaution later reflected in EU rules.

Also known as

butyl parabenbutyl 4-hydroxybenzoate

CAS numbers

94-26-8

Commonly found in

lotionsunscreenmakeupdeodorant

Safer alternatives

  • phenoxyethanol
  • sodium benzoate
  • ethylhexylglycerin

Related chemical families

Parabens

Sources

  • Routledge et al. 1998
  • Danish Statutory Order on Parabens 2011