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Medium concernColorant

D&C Red 22

AllergenSkin irritant

What it is

A brominated fluorescein dye with bright pink fluorescence.

What it does

Colourant in lipsticks and some toothpastes.

Why it’s a concern

Contains bromine as part of the molecule; can cause contact sensitisation and photosensitivity in some individuals. Older literature documents allergic cheilitis from lipstick use. Long-term ingestion safety is limited by available data.

Also known as

red 22eosin YCI 45380

CAS numbers

17372-87-1

Commonly found in

lipsticktoothpaste

Safer alternatives

  • iron oxides
  • plant-based pigments

Sources

  • FDA 21 CFR 74.1322