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High concernPreservative

Diazolidinyl Urea

Formaldehyde releaserKnown carcinogenAllergen

What it is

A urea-derived heterocyclic preservative that decomposes to release formaldehyde.

What it does

Broad-spectrum antimicrobial for water-based cosmetics, often combined with parabens or phenoxyethanol.

Why it’s a concern

Among the most common formaldehyde releasers associated with allergic contact dermatitis in North American Contact Dermatitis Group patch-test data. The release of formaldehyde, a Group 1 carcinogen, is the core concern even if concentrations stay within regulatory limits.

Also known as

germall II

CAS numbers

78491-02-8

Commonly found in

lotionshampoomakeupbaby wipes

Safer alternatives

  • sodium benzoate
  • potassium sorbate
  • phenoxyethanol at low levels

Related chemical families

Formaldehyde

Sources

  • NACDG Patch Test Data 2019-2020