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High concernPreservative

Methyldibromo Glutaronitrile

AllergenSkin irritant

What it is

A brominated nitrile preservative once widely used with phenoxyethanol (Euxyl K 400).

What it does

Broad-spectrum antimicrobial in cosmetics and wipes.

Why it’s a concern

Banned in EU leave-on cosmetics in 2005 and in rinse-off products in 2007 following a European epidemic of severe contact allergy during the late 1990s. Serves as a cautionary case for how rapidly a new preservative can become a leading allergen when widely adopted.

Also known as

MDBGN1,2-dibromo-2,4-dicyanobutane

CAS numbers

35691-65-7

Commonly found in

older cosmeticsindustrial products

Safer alternatives

  • phenoxyethanol alone
  • sodium benzoate

Sources

  • SCCNFP Opinion SCCNFP/0849/04