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Medium concernSurfactant

Polysorbate 80

Skin irritant

What it is

An ethoxylated sorbitan ester derived from sorbitol and oleic acid.

What it does

Emulsifier and solubiliser in foods, vaccines, and cosmetics.

Why it’s a concern

Ethoxylation creates the potential for 1,4-dioxane and ethylene oxide contamination. A 2015 study (Chassaing et al., Nature) suggested polysorbate 80 and carboxymethylcellulose disrupted gut microbiota and promoted intestinal inflammation in mouse models at dietary-relevant doses.

Also known as

tween 80polyoxyethylene sorbitan monooleate

CAS numbers

9005-65-6

Commonly found in

ice creamvaccineslotionprocessed food

Safer alternatives

  • non-ethoxylated emulsifiers (lecithin, cetearyl olivate)

Related chemical families

Vocs

Sources

  • Chassaing et al. 2015, Nature